Car-NK cell therapy for lupus
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This trial tests a new immune cell therapy (CAR NK cells) for people with moderate to severe lupus that hasn't responded well to standard treatments. The therapy targets a protein called CD19 on certain immune cells to calm the overactive immune system.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have a diagnosis of lupus that is still active despite treatment with steroids and at least one other lupus medication for at least 6 months
- Your lupus disease activity score is 8 or higher on the SLEDAI scale, which is a measure of lupus severity
- You have at least one organ system (like kidneys, skin, or joints) with moderate to severe inflammation, as measured by the BILAG system
- Your blood counts (neutrophils and hemoglobin) are within a safe range
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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