Testing vagus nerve stimulation for motivation in depression
Part of Brain & nervous system clinical trials.
This trial tests if a gentle nerve stimulation device can improve motivation and interest in people with depression and a lack of pleasure or drive. You keep taking your usual antidepressant pill during the study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with major depression and have low motivation or loss of interest
- Score high on standard depression and apathy rating scales
- Currently taking only a type of antidepressant called an SSRI (like fluoxetine or sertraline)
- Between 18 and 60 years old, with at least 6 years of education
- Right-handed, normal vision, and no prior brain stimulation treatments
- No history of seizures, head injury, neurological disorders, or metal implants in the head
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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