Nerve response study in piezo2 gene mutation
Part of Brain & nervous system, Genetic & congenital clinical trials.
This study uses a tiny probe to measure how your nerves respond to touch and pain. It compares healthy people with those who have a rare genetic condition (PIEZO2) that affects sensation, to understand why some people feel touch differently.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older
- You must already be enrolled in the NIH pain study (protocol 16-AT-0077)
- You either have a confirmed PIEZO2 gene mutation causing sensory problems, or you are a healthy volunteer
- You must not have chronic pain, nerve damage, or be taking nerve pain medications
- You must not have serious medical conditions like heart disease, diabetes, or untreated depression
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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