Bariatric Surgery and its Effects on Fat, Immune Cells, and Cancer
Part of Hormones & metabolism clinical trials.
This study looks at how bariatric (weight-loss) surgery affects fat metabolism, immune cells, and cancer risk in women with severe obesity and high cholesterol. If you are a woman aged 35–60, White or Black, with a BMI of 40 or higher and high triglycerides or LDL, you may be eligible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 35 and 60 years old.
- You are White or Black (the study aims to include equal numbers of each).
- Your BMI is 40 or higher (severe obesity).
- You have high triglycerides or LDL cholesterol, or you take medication for it.
- You are scheduled for bariatric surgery but have not yet started the pre-op liquid diet.
- You do not have diabetes, history of cancer, or chronic inflammatory conditions.
- You have not taken anti-inflammatory drugs (like ibuprofen or steroids) in the past 15 days.
- You are not on any prescription weight-loss medication (like Wegovy, Saxenda, or Contrave).
- You are not pregnant, breastfeeding, or planning pregnancy in the next year.
- You have not had COVID-19 in the past 60 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
This trial looks at obesity care in people who have already had bariatric (weight-loss) surgery or certain abdominal surgery. It may help researchers understand what treatments or follow-up care could work best for you after surgery.
This trial looks at proteins in the blood of people having bariatric surgery to understand how the surgery affects the body. It may help find ways to improve outcomes.
This study looks at how inflammation affects heart disease and diabetes. It may help find new ways to prevent or treat these conditions.
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.