Clin2
NCT06081959Possibly a fitRecruiting

Study of SKB264 for advanced HR+/HER2- breast cancer

Metastatic Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests a new drug called SKB264 for people with a common type of breast cancer (HR+/HER2-) that has spread or come back and has not responded to at least one round of chemotherapy. It aims to see if this treatment can help shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
376 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with HR+/HER2- breast cancer that has spread or come back and is not removable by surgery.
  • You have had at least one type of chemotherapy that no longer works for your advanced cancer.
  • You have a tumor that can be measured on scans (not just skin or bone spots).
  • You are well enough to be up and about (ECOG score 0 or 1) and expected to live at least 12 more weeks.
  • You agree to use effective birth control if you or your partner could become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07071337Recruiting· Phase 3
Study of SKB264 vs chemo for HR+/HER2- breast cancer after hormone therapy

This trial tests a new drug, SKB264, against standard chemotherapy for people with a common type of breast cancer (HR+/HER2-) that has spread and stopped responding to hormone therapy. It may offer a new option if you haven't had chemotherapy for advanced disease.

Beijing, Beijing Municipality
NCT06383767Recruiting· Phase 3
A study of ESG401 for advanced HR+/HER2- breast cancer

This trial tests a new medicine called ESG401 for people with a common type of breast cancer (HR+/HER2-) that has spread and hasn't responded to at least one chemotherapy. The goal is to see if it works better than standard chemotherapy options.

Beijing, Beijing Municipality
NCT06993506Recruiting
SKB264 alone or combined for advanced HER2- breast cancer

This study is a real-world treatment trial for people with advanced HER2-negative breast cancer (either triple-negative or HR+/HER2-). It tests a drug called SKB264, given alone or with other therapies, and aims to see how well it works in everyday clinical practice.

Hefei, Anhui
NCT06279364Recruiting· Phase 3
Testing SKB264 vs standard chemo for advanced triple-negative breast cancer

This trial tests a new drug called SKB264 against standard chemotherapy options for people with advanced triple-negative breast cancer who have not yet received chemotherapy for their advanced disease. The goal is to see if SKB264 works better than the usual treatments.

Shanghai, Shanghai Municipality
NCT07774624Not yet recruiting· Phase 1/Phase 2
Study of an experimental drug for HER2-negative breast cancer

This trial tests a new drug, SKB103, for people with HER2-negative breast cancer that has not responded to standard treatments. The goal is to see if the drug can help shrink tumors or slow the cancer's growth.

NCT06942234Recruiting· Phase 1/Phase 2
Study of JSKN016 for advanced HER2-negative breast cancer

This trial tests a new combination drug (JSKN016) for people with HER2-negative breast cancer that has spread or cannot be removed. It is for those who have not yet had advanced-stage treatment (except hormone therapy) and may offer a new option.

Shanghai

Hear when a new Metastatic Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.