Low-dose capecitabine for advanced breast cancer
Part of Cancer, Skin clinical trials.
This trial tests a lower dose of the chemotherapy drug capecitabine in people with advanced breast cancer that is HER2 negative. It aims to see if this gentler dose works well, especially for older or frailer patients who may have more difficulty with standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have breast cancer that has spread to other parts of the body or is locally advanced and cannot be removed by surgery.
- Your cancer is HER2 negative, meaning it does not have high levels of the HER2 protein.
- You have tried at least one prior treatment for advanced breast cancer (hormone therapy or chemotherapy) and it stopped working.
- You are age 60 or older, or at any age are considered frail by your doctor (more risk of side effects from standard treatment).
- You have at least one tumor that can be measured on scans.
- You have adequate kidney and liver function, and your blood cell counts are within a safe range.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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