Non-opioid pain control after fracture surgery
Part of Injuries & trauma clinical trials.
This trial tests a combination of non-opioid medications to manage pain after surgery for a broken bone, aiming to reduce or avoid the use of opioids. It may help you control pain without the risks of strong painkillers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are scheduled for surgery to fix a broken bone (open reduction internal fixation) at Henry Ford Hospital in Detroit or West Bloomfield, Michigan
- You do not have allergies or intolerance to ibuprofen (Motrin), pregabalin (Lyrica), acetaminophen (Tylenol), tramadol, or tizanidine (Zanaflex)
- You have not had significant alcohol or drug problems
- You are not pregnant
- You have not taken opioid pain medications in the 6 months before surgery
- You do not have kidney problems, stomach ulcers, or a history of stomach bleeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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