Clin2
NCT06118086Possibly a fitRecruiting

Study of REM-422 for advanced adenoid cystic carcinoma

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic CarcinomaRecurrent Adenoid Cystic Carcinoma

Part of Cancer clinical trials.

This trial tests an experimental drug called REM-422 for people with adenoid cystic carcinoma (ACC) that has spread, come back, or cannot be removed by surgery. The study has two parts: an early part for people with advanced ACC and a later part for those with a specific genetic change (MYB biomarker) in their tumor. The goal is to see if REM-422 can slow or stop cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
125 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have adenoid cystic carcinoma that has spread, come back, or cannot be surgically removed.
  • Your cancer must be worsening, or you must have symptoms from it.
  • For the later part of the study, your tumor must have a specific genetic change called MYB positive.
  • You must be able to swallow pills and have had no major stomach or bowel surgery that affects absorption.
  • You must agree to use effective birth control if you could become pregnant or father a child.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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