Vitamin B1 movement in people with and without an active OCT1 transporter
This study checks how vitamin B1 (thiamin) moves through the body in healthy people. It compares two groups: those with a normal OCT1 liver transporter and those with a less active one. The goal is to see if genetics affect how your body handles vitamin B1.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 50 years old
- You need to have a known OCT1 gene type (either a good transporter or a poor transporter)
- You should be generally healthy or have only mild, well-controlled conditions like allergies or high blood pressure
- You can take up to 3 prescription medications that don't interact with OCT1
- You cannot be pregnant, breastfeeding, or taking regular vitamin B1 supplements without a 48-hour break before visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This phase 1 study tests an experimental drug called TIX100 in healthy volunteers to check its safety and how the body processes it. The results will help determine if the drug can be studied in future trials for conditions like obesity or metabolic disorders.
This study tests how a new medicine, BI 3000202, is absorbed into the blood. It includes people with different levels of liver function (normal, mild, moderate, or severe) to see if liver problems affect how the medicine works.
This Phase 1 study tests how a new medicine (TBN) behaves in the body after several doses, including side effects and tolerability. It is meant for healthy adults to help researchers decide how it can be used safely in future studies.
This trial tests a new drug called CAY001 in healthy volunteers to see how safe it is and how the body processes it. It may help researchers understand if the drug is safe enough to test in people with medical conditions later.
This Phase 2 study tests whether taking thiamine and biotin together can improve symptoms in people with Huntington’s disease. It looks especially at people with confirmed genetic Huntington’s disease and certain types of movement and/or mood symptoms.
This study looks at how the body processes vitamin E when blood fat levels are high or normal. It may help researchers understand how vitamin E works in different people.
Hear when a new Healthy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.