Vitamin B1 for familial adenomatous polyposis
Part of Cancer, Digestive system, Genetic & congenital clinical trials.
This trial tests whether taking vitamin B1 can help people with familial adenomatous polyposis (FAP) reduce the number of polyps in their colon or rectum. It is designed for people who still have most of their bowel and have more than 10 polyps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of classic familial adenomatous polyposis (FAP).
- You must be between 18 and 80 years old.
- You must not have had your entire colon removed (no total colectomy).
- You must have more than 10 adenomatous polyps in your colon or rectum.
- You must have normal liver and kidney function and be willing to take vitamin B1 and attend follow-up appointments.
- You cannot have taken certain medications that affect polyps or vitamin B1 (like aspirin, NSAIDs, or certain antibiotics) for more than a week in the past 3 months.
- You must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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