Vitamin B1 supplement to lessen brain damage from heavy drinking
Part of Mental health clinical trials.
This study tests whether giving vitamin B1 (thiamine) to people who drink heavily can reduce alcohol-related brain injury. It may help protect memory and thinking if you are currently drinking a lot.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with moderate to severe alcohol use disorder.
- You drink at least 40 grams of alcohol per day (roughly 3-4 standard drinks).
- You have not taken thiamine (vitamin B1) supplements in the past month.
- You are not planning to be hospitalized or have surgery during the study.
- You do not have severe liver or kidney disease, active infections like HIV or hepatitis C, or a recent history of seizures, stroke, or serious head injury.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
This trial tests a program to improve memory and thinking skills in people with alcohol use disorder. It may help support recovery and daily functioning.
This trial tests a type of noninvasive brain stimulation to see if it can reduce drinking and related “wanting” to drink. It may help people with alcohol use disorder who are currently drinking heavily.
This study looks at whether alcohol use disorder affects the cerebellum, a part of the brain involved in movement and balance. It may help researchers understand brain impacts and guide better treatments.
This study tests if a blood-pressure medicine called nimodipine can help people who drink heavily reduce their alcohol intake. The trial involves lab-based drinking sessions and brain scans to understand how the drug works on the brain.
Hear when a new Alcohol Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.