Radiation timing for advanced esophageal cancer with limited spread
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving radiation all at once or in two stages works better for people with esophageal cancer that has spread to only a few spots. It aims to find the safest and most effective way to use radiation to control the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with squamous cell carcinoma of the esophagus (a type of esophageal cancer).
- Your cancer has spread to 5 or fewer distant spots (like other organs or lymph nodes), and each spot is smaller than 5 cm.
- You are in generally good health (able to do daily activities) and have not lost more than 10% of your body weight in the last 6 months.
- You have not had chemotherapy, radiation, or immunotherapy for any cancer in the past 6 months.
- Your blood counts, kidney function, and liver function are within acceptable ranges (your doctor can check these).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether adding an anti-PD-1 immunotherapy (with chemotherapy) together with radiation can help people with advanced esophageal squamous cell cancer. It’s for cases where surgery or standard definitive chemoradiation can’t be done, or the cancer has spread to distant sites.
This trial tests different combinations of treatments given before surgery for a type of esophageal cancer called squamous cell carcinoma. It aims to find the best approach to shrink the tumor and improve outcomes for patients whose cancer has not spread to distant organs.
This trial tests a short course of radiation combined with two drugs (raltitrexed and tislelizumab) for people with esophageal cancer that has returned after standard treatment. The goal is to see if these combinations can shrink tumors and improve survival.
This trial tests whether giving local treatments (like surgery or radiation) to cancer spots later—after starting immunotherapy or targeted therapy—helps people with stomach or esophageal cancer that has spread to a few places. It aims to improve outcomes by timing treatments carefully.
This trial tests a new approach for advanced esophageal cancer that combines targeted radiation, immunotherapy, and chemotherapy. It aims to see if skipping radiation to certain lymph nodes can improve outcomes while reducing side effects.
This trial tests whether adding radiation therapy to a standard treatment (immunotherapy plus chemotherapy) can help people with advanced esophageal cancer that has spread to up to two organs. The goal is to see if the combination improves outcomes.
Hear when a new Advanced Esophageal Squamous Carcinoma With Oligometastases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.