Testing a Glowing Dye to Improve Brain Tumor Removal
Part of Brain & nervous system, Cancer clinical trials.
This trial compares two surgical techniques for removing malignant brain tumors: one using a special dye (5-ALA) that makes tumor cells glow under a blue light, versus the standard white light surgery. The goal is to see if the dye-guided approach helps surgeons remove more of the tumor safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have a newly diagnosed malignant glioma (a type of aggressive brain tumor) that is grade 3 or 4.
- Your overall health status allows you to perform daily activities without needing bed rest more than half the day (KPS score of 60 or higher).
- You are able to swallow pills.
- You do not have porphyria or a history of severe skin reactions to light.
- Your tumor is not located in the brainstem, deep brain areas, or cerebellum.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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