Glowing dye during surgery for children's brain tumours
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a drug called 5-ALA that makes brain tumor cells glow under a special light during surgery. This helps surgeons see and remove more of the tumor safely, potentially improving outcomes for children with high-grade brain tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 3 to 18 years.
- Have a high-grade brain tumor (either newly diagnosed or a return of ependymoma or high-grade glioma).
- Tumor is located in the upper or lower back part of the brain, not in the brainstem.
- Doctor has planned surgery to remove as much of the tumor as possible.
- Good liver and kidney function, normal blood clotting, and normal blood pressure.
- No personal or family history of porphyria (rare blood disorder causing light sensitivity), and no known sensitivity to light or to porphyrins.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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