Adding lumateperone to clozapine for schizophrenia
Treatments studied
Part of Mental health clinical trials.
This trial tests whether adding lumateperone, an antipsychotic medication, to clozapine can improve metabolic health in people with schizophrenia. It aims to see if this combination helps with weight, blood sugar, and cholesterol levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have schizophrenia or schizoaffective disorder.
- You've been taking clozapine for at least 6 months.
- Your dose of antipsychotic medication has been stable for the past month.
- You are not pregnant or breastfeeding, and if you could become pregnant, you agree to use birth control.
- You do not have a current substance use disorder (other than caffeine or nicotine).
- You have not taken lumateperone or similar drugs (aripiprazole, brexpiprazole, cariprazine) in the past 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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