Testosterone treatment for low ovarian reserve
Part of Hormones & metabolism clinical trials.
This trial tests whether taking testosterone before IVF can improve egg quality and pregnancy chances in women with low ovarian reserve. It is specifically for women with a certain genetic marker in the androgen receptor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 40 or older, or have had a previous IVF cycle with fewer than 4 eggs retrieved, or have low ovarian reserve markers (AMH less than 0.5-1.1 ng/ml or antral follicle count less than 5-7).
- You carry a specific genetic variant in the androgen receptor gene (between 22 and 24 CAG repeats).
- Your body mass index (BMI) is under 32.
- You have both ovaries and no ovarian cysts or endometriosis.
- You have normal karyotype (chromosomes) and fragile X test results.
- You are planning IVF and your partner's semen sample comes from ejaculation (not surgical extraction).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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