Testosterone for women with low ovarian reserve and a specific gene variation
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study tests whether giving testosterone to women with low ovarian reserve and a specific genetic variation in their androgen receptor can improve IVF outcomes. It may help women who have not responded well to previous fertility treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 or older, or have had fewer than 4 eggs retrieved in a past IVF cycle, or have low ovarian reserve markers (like low AMH or antral follicle count).
- You have a specific genetic variation in your androgen receptor (between 22 and 24 CAG repeats).
- Your BMI is under 32.
- You have both ovaries, no ovarian cysts, and no endometriosis.
- Your partner's sperm can be collected from ejaculate (no severe male factor).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a medication called etanercept, which reduces inflammation, can improve the chances of having a baby for women with low ovarian reserve who are doing IVF. It may help by making the womb more receptive to embryos.
This study tests a special injection of growth factors from your own blood into the ovary to see if it can improve egg quality and quantity for women with low ovarian reserve. It may be an option if you have been trying to conceive for over a year and have low egg reserve.
This trial tests whether adding growth hormone and DHEA to your IVF medications can help women with low ovarian reserve get more eggs and improve pregnancy chances. It may be an option if you are over 40, have had few eggs before, or have low egg count markers.
This study tests a different type of fertility medication to help women who had fewer than 9 eggs retrieved in a previous IVF cycle. It's designed for women between 18 and 40 with a specific hormone profile, and aims to improve egg collection results.
This trial tests whether a special herbal formula, given before an IVF cycle, can improve pregnancy success in women with diminished ovarian reserve. It is for women who are aged 22 to 39, have low egg supply, and have a Traditional Chinese Medicine diagnosis of Kidney Deficiency.
This trial tests whether taking Coenzyme Q10 before IVF helps women who are known to respond poorly to ovarian stimulation, with the goal of improving egg quality and pregnancy outcomes.
Hear when a new Fertility Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.