Clin2
NCT07816562Possibly a fitRecruiting

Ovulation trigger options for women with low ovarian reserve

Low Ovarian ReservePoor Ovarian Response

Treatments studied

Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study compares two different medications used to trigger ovulation in women with low ovarian reserve who are undergoing fertility treatment. The goal is to find which approach leads to better outcomes, such as more eggs retrieved and higher pregnancy chances.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
126 people
Ages
18 years to 42 years
Study type
Interventional

Who can take part

  • You are a woman between 18 and 42 years old.
  • You have been diagnosed with primary infertility (never been pregnant before).
  • You have low ovarian reserve as defined by the POSEIDON criteria (a classification system for women with reduced egg supply).
  • You have not had more than two previous failed fertility stimulation cycles.
  • Your body mass index (BMI) is 35 or lower.
  • Your male partner is 55 years old or younger, and does not have severe male factor infertility (total motile sperm count of at least 1 million).
  • You have not had a previous sterilization (like tubal ligation) and do not have a healthy child together with your current partner.
  • You do not have any medical conditions that would make pregnancy unsafe, and you are not at high risk for ovarian hyperstimulation syndrome (OHSS).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06975683Recruiting
PRGF ovarian injection for low ovarian reserve

This study tests a special injection of growth factors from your own blood into the ovary to see if it can improve egg quality and quantity for women with low ovarian reserve. It may be an option if you have been trying to conceive for over a year and have low egg reserve.

Madrid
NCT06195163Not yet recruiting· Phase 4
Testosterone treatment for low ovarian reserve

This trial tests whether taking testosterone before IVF can improve egg quality and pregnancy chances in women with low ovarian reserve. It is specifically for women with a certain genetic marker in the androgen receptor.

Alicante, Alicante
NCT06433518Recruiting
Comparing trigger shot sizes for older women with low egg reserve

This trial compares two different trigger shot sizes for women 35 and older who have low egg reserve. The goal is to find which trigger dose leads to the best egg retrieval results.

Ankara, Ankara
NCT07121751Not yet recruiting· Phase 4
Improving egg collection for low responders in IVF treatment

This study tests different medication approaches to help women who had a low number of eggs in a previous IVF cycle produce more eggs this time. The goal is to find a better stimulation method for women with this 'low response' pattern.

Budapest
NCT07569289Not yet recruiting· Phase 2
Oocyte maturation trigger for poor responders in IVF

This trial tests two different ways to trigger the final maturation of eggs before retrieval in women who are considered poor responders to IVF treatment. It aims to see if a double trigger is more effective than the standard HCG trigger for improving egg and embryo outcomes.

Giza, Giza Governorate
NCT07771283Enrolling by invitation
Comparing ovarian stimulation methods for IVF

This study compares two methods of stimulating the ovaries before IVF: one using a standard hormone (hCG) and another using a different protocol. The goal is to see if the new method works as well as the standard one, while possibly being more cost-effective.

Kampala

Hear when a new Poor Ovarian Response trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.