Study of a new nano-medication for infected tooth root canals
Treatments studied
Part of Mouth & dental clinical trials.
This trial tests whether a nano-scale calcium hydroxide paste works better than standard treatments for tooth infections. If you have a permanent molar with signs of infection around the root tip, this study may be an option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy adult aged 21 to 49.
- You have a permanent back tooth (molar) with signs of infection around the root tip.
- You have no physical or psychological conditions that would affect your participation.
- You have not taken antibiotics in the past month.
- You are not pregnant and have no serious immune system or other medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new, nano-sized antimicrobial gel to fight stubborn infections during repeat root canal treatment. It's for people with a premolar that still hurts or shows signs of infection after a previous root canal.
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
This study tests a new type of nanoparticle (tiny medical particles) called Ferumoxytol to help treat infected tooth roots. Researchers want to see if this approach works better than standard root canal treatments.
This trial looks at how well a dentist’s treatment works for a combined gum and tooth infection (“endodontic-periodontal disease”) using calcium filling material, with or without extra biologic material. If you qualify, it may help improve the health of deep gum pockets and support better healing around affected tooth roots.
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
This trial tests a regenerative endodontic procedure—a newer approach to treat mature teeth with dead nerve tissue and chronic inflammation at the root tip. The goal is to help your tooth heal and potentially restore its vitality without a traditional root canal.
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