Clinical trials
Endodontic Disease clinical trials
Below are recruiting endodontic disease clinical trials, each written for real people, not researchers. We’re tracking 10 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06643663Recruiting
Gum surgery for teeth with gum disease and failed root canal
This study tests a gum surgery technique (guided tissue regeneration) to help heal teeth that have both gum disease and a failed root canal. It looks at how well the tooth heals and how it affects your daily life.
HaryānaAges 16 years+ - NCT06574152Recruiting
Light therapy for pain relief after dental root surgery
This trial tests whether a special light treatment, called photobiomodulation, can help reduce pain and speed up healing after a specific type of dental surgery on the root of a tooth. The surgery involves a small cut in the gum, and the light may help the gum recover faster.
Houston, TexasAges 18 years+ - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+ - NCT04527705Recruiting
Testing endodontic retreatment in one versus two visits
This study compares doing tooth root-canal retreatment in one visit versus two visits. It’s meant to see which approach leads to better outcomes for teeth with infection at the root tip (apical periodontitis).
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT04528979Recruiting
Tests a bioceramic filling material for root-canal treatment outcomes
This study looks at how well a bioceramic sealing material works for tooth root-canal treatment, including cases where previous treatment did not work. If you have certain types of tooth nerve inflammation or infection, you may be eligible to help compare outcomes and improve care.
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT07518901Enrolling by invitationPhase 4
New Nanoparticle Treatment for Root Canal Therapy
This study tests a new type of nanoparticle (tiny medical particles) called Ferumoxytol to help treat infected tooth roots. Researchers want to see if this approach works better than standard root canal treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06660797Recruiting
Irrigation methods for root canal treatment
This trial tests different ways to flush and clean inside a tooth during root canal treatment. It aims to see which method best reaches deep into the tooth and reduces bacteria.
TantaAges 18–40 - NCT07448571Recruiting
Testing i-PRF for better root canal retreatment healing
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
IstanbulAges 18–50 - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+
Hear when a new Endodontic Disease trial opens
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Common questions
- Are there clinical trials for endodontic disease?
- Yes. Clin2 currently lists 10 recruiting endodontic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endodontic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endodontic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.