Clin2
NCT06208735Possibly a fitRecruiting

CLIC-2201 for relapsed or refractory B cell cancers

B-Cell LeukemiaNon-Hodgkin's LymphomaB-cell Acute Lymphoblastic LeukemiaDiffuse Large B Cell LymphomaHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)Mantle Cell LymphomaB-cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This trial tests a new treatment called CLIC-2201 for people with certain types of B cell lymphoma or leukemia that have come back or not responded to previous treatments. It aims to see if this therapy can help control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
1 year and older
Study type
Interventional

Who can take part

  • You must be 18 or older (for the adult group) or between 1 and 39 years old (for the pediatric/young adult group).
  • You must have a type of B cell lymphoma or B cell acute lymphoblastic leukemia that has returned or not responded to at least 2 prior treatments, or has returned after a stem cell transplant or CAR-T therapy.
  • Your heart, kidneys, and liver must be working well enough, as checked by tests.
  • You must be able to care for yourself (performance status of 0-2 on the ECOG scale or a Karnofsky/Lansky score of at least 50%).
  • You must agree to use effective birth control for at least one year after treatment if you are of reproductive age.
  • You must be willing to have a tumor or bone marrow biopsy before starting the trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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