Clin2
NCT06180174Possibly a fitRecruiting

CD19-targeted CAR-T cells for relapsed B-cell lymphoma

B Cell LymphomaNon Hodgkin Lymphoma

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a new type of immune cell therapy (CAR-T cells) that targets a protein called CD19 on your lymphoma cells. It's for people whose B-cell lymphoma has returned or not responded to standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have a type of B-cell lymphoma that has come back or not gotten better after treatment.
  • Your cancer cells have a protein called CD19.
  • You are in fairly good health, with no major heart, kidney, or liver problems.
  • You have not had CAR-T therapy before and are not pregnant or planning pregnancy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07009002Recruiting· Phase 1/Phase 2
Modified CAR-T cell therapy for relapsed B-cell lymphoma

This study tests a new kind of CAR-T cell therapy for people with certain types of B-cell lymphoma that have come back or not improved after standard treatments. The CAR-T cells have been modified to turn off two genes (BCOR and ZC3H12) to make them work better against the cancer.

Beijing, Beijing Municipality
NCT06081478Recruiting· Phase 2
Targeted CAR-T cell therapy for advanced lymphoma or leukemia

This trial tests a new type of immune cell therapy (CAR-T) that targets two proteins on cancer cells—CD19 and CD22—to treat lymphoma or leukemia that has come back or not responded to standard treatment. It aims to see if this two-target approach works better.

Beijing, Beijing Municipality
NCT05098613Recruiting· Phase 1
Testing a new immune cell therapy for relapsed B-cell lymphoma

This trial is testing a new treatment called CD19x22 CAR T cells for people with certain types of B-cell lymphoma that have come back or not responded to other treatments. The therapy uses your own immune cells, which are modified in a lab to better attack the cancer.

Aurora, Colorado
NCT06838832Recruiting· Phase 1/Phase 2
New CAR-T cell therapy for relapsed B-cell lymphoma

This trial tests a new treatment made from your own immune cells (gamma-delta T cells) that are engineered to find and kill CD19-positive lymphoma cells. It is for people with B-cell non-Hodgkin lymphoma whose cancer has not responded to or has returned after at least two standard treatments.

Beijing, Beijing Municipality
NCT05554939Recruiting· Phase 1/Phase 2
CAR-T cells targeting CD19 for relapsed B-cell lymphoma

This Phase 1/2 trial studies an “off-the-shelf” (allogeneic) immune-cell therapy that targets CD19, a marker on many B-cell lymphomas. It’s for adults whose lymphoma has come back or didn’t respond to prior treatment, aiming to shrink tumors and improve outcomes.

Beijing, Beijing Municipality
NCT07344818Recruiting· Early Phase 1
CAR-T cell therapy targeting CD19 and CD20 for hard-to-treat B-cell lymphoma

This early-stage study tests a new type of immune cell therapy (CAR-T) that targets two proteins, CD19 and CD20, on your lymphoma cells. It is for people with aggressive B-cell lymphoma that has returned or not responded after several treatments. The goal is to see if this therapy can help shrink the cancer.

Beijing, Beijing Municipality

Hear when a new Lymphoma, B-Cell trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.