Immunotherapy maintenance after surgery for head and neck cancer
Treatments studied
Part of Cancer clinical trials.
This trial looks at whether continuing immunotherapy can help keep cancer from coming back in people with head and neck cancer who had a good response to chemo-immunotherapy before surgery. You would have already had surgery, and now the study tests a maintenance treatment to strengthen your immune system's fight against any remaining cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old.
- You have head and neck squamous cell cancer that has not spread to other parts of the body.
- After surgery, your tumor showed a major response (called MPR) to the chemo-immunotherapy you received before surgery.
- You are in good general health (able to do daily activities without major limitations).
- You do not have an active autoimmune disease, a serious infection, or active hepatitis B/C.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 2 study looks at what treatment is best after you first receive chemotherapy plus immunotherapy, then have surgery for head and neck squamous cell cancer. It tries to use how your tumor responds (shown in lab tissue after treatment) to guide the next steps, which may improve outcomes.
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This Phase 2 trial tests toripalimab (an immunotherapy drug) given as maintenance to help keep locally advanced head and neck squamous cell cancer from coming back after you have no remaining visible tumor. It may help the immune system stay alert and improve outcomes after standard treatment.
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