Epcoritamab for B-cell lymphoma after CAR-T therapy
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests if the drug epcoritamab can help people with B-cell lymphoma whose cancer showed only a partial response 30 days after CAR-T cell therapy. It compares epcoritamab to simply monitoring the condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older with a type of B-cell lymphoma (like diffuse large B-cell lymphoma) that tested positive for CD20 within the last 6 months.
- You must have received one of three specific CAR-T cell therapies (axicabtagene ciloleucel, tisagenlecleucel, or lisocabtagene maraleucel) and had only a partial response at day 30.
- You must have measurable disease that can be seen on a PET-CT scan.
- Your overall health must be good enough to carry out daily activities (ECOG score 0, 1, or 2).
- Your blood counts and organ function (kidney, liver, heart) must meet minimum levels as tested within 14 days before enrolling.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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