Clin2
NCT06247046Likely a fitRecruiting

Probiotic powder for IBS-D (SK08) trial

Irritable Bowel Syndrome With Diarrhea

Part of Digestive system clinical trials.

This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
1,298 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • Must be 18 to 70 years old
  • Diagnosed with IBS with diarrhea (IBS-D) for at least 6 months, with belly pain and loose stools most days for the past 3 months
  • Had a colonoscopy in the past year (with or without small polyps removed) – and your IBS symptoms have continued since then
  • During a 2‑week run‑in period, you had loose stools at least 4 days per week and your daily belly pain score averaged at least 3 out of 10 on those days
  • No other serious health conditions (like heart, kidney, autoimmune disease, or poorly managed diabetes/thyroid), no abdominal/pelvic surgery (except simple ones), and no current or recent use of certain gut‑affecting medications

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06612411Recruiting· Early Phase 1
Testing a probiotic for diarrhea-predominant IBS

This trial tests whether a specific probiotic (Bacillus subtilis) can help relieve symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS). The study also looks at whether the probiotic works by increasing a natural chemical called hypoxanthine in the body.

Nanjing
NCT06271538Recruiting· Phase 4
Skal Pro Powder for IBS symptoms

This study tests if Skal Pro Powder, a probiotic, can help relieve symptoms of Irritable Bowel Syndrome (IBS). It is for adults with any type of IBS who haven't used certain other treatments recently.

Kubang Kerian, Kelantan
NCT06725017Not yet recruiting· Phase 2
Live SK08 powder for mild to moderate ulcerative colitis

This study tests if a live bacterial powder (SK08) can help people with active mild to moderate ulcerative colitis. It aims to see if it improves symptoms and is safe to take.

NCT06636513Recruiting
Testing SMT04 for irritable bowel syndrome

This trial tests a new treatment called SMT04 for people with irritable bowel syndrome (IBS), specifically the diarrhea or mixed types. It may help reduce symptoms like abdominal pain and changes in bowel habits.

Singapore, Singapore
NCT06647043Recruiting
Can synbiotics help irritable bowel syndrome?

This study tests whether a synbiotic (a mix of good bacteria and fiber) can improve symptoms of irritable bowel syndrome (IBS), especially for people with diarrhea-predominant or mixed type IBS, or functional diarrhea.

Kubang Kerian, Kelantan
NCT07584278Recruiting
Probiotics and Biomarkers for Irritable Bowel Syndrome

This study tests whether probiotics (beneficial bacteria) can help reduce irritable bowel syndrome (IBS) symptoms and change certain markers in your gut. You'll take a probiotic supplement for 12 weeks while researchers track how your symptoms and gut health change.

Gothenburg

Hear when a new Irritable Bowel Syndrome - Diarrhoea trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.