Clinical trials
Irritable Bowel Syndrome - Diarrhoea clinical trials
Below are recruiting irritable bowel syndrome - diarrhoea clinical trials, each written for real people, not researchers. We’re tracking 113 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07793487Enrolling by invitation
Testing a special dairy drink for gut and metabolic health
This study tests whether a special dairy product can help improve symptoms in people with irritable bowel syndrome or early signs of metabolic syndrome. Participants must be at a healthy weight and not have other major health conditions or be on certain diets.
WarsawAges 18 years+ - NCT06788444Recruiting
Esketamine for irritable bowel syndrome with anxiety or depression
This study tests if esketamine, a fast-acting medication, can help people with irritable bowel syndrome who also have anxiety or depression. It is given during a colonoscopy to see if it reduces your IBS symptoms.
Beijing, Beijing MunicipalityAges 18–60 - NCT06668922Recruiting
Diet and irritable bowel syndrome study
This study compares how people with and without irritable bowel syndrome (IBS) react to different foods. It may help find which foods trigger symptoms and which are safe to eat.
Los Angeles, CaliforniaAges 18–75 - NCT06612411RecruitingEarly Phase 1
Testing a probiotic for diarrhea-predominant IBS
This trial tests whether a specific probiotic (Bacillus subtilis) can help relieve symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS). The study also looks at whether the probiotic works by increasing a natural chemical called hypoxanthine in the body.
NanjingAges 16–80 - NCT06104631Recruiting
Testing a treatment for IBS-like symptoms in Crohn's remission
This study tests whether a new treatment can reduce IBS-like symptoms, such as belly pain and bloating, in people whose Crohn's disease is in remission. It aims to improve your quality of life without targeting active Crohn's inflammation.
LiègeAges 18–75 - NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT06737666RecruitingPhase 1
Tong-Xie-Yao-Fang for Diarrhea-Predominant IBS
This trial tests an herbal formula called Tong-Xie-Yao-Fang for people with diarrhea-predominant irritable bowel syndrome (IBS-D). It aims to see if the treatment helps symptoms and how it works. Healthy volunteers are also needed for comparison.
Beijing, Beijing MunicipalityAges 18–70 - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT03339128RecruitingPhase 2
Eluxadoline for diarrhea-predominant IBS in children
This trial tests whether eluxadoline can reduce symptoms of IBS with diarrhea (IBS-D) in children ages 6 to 17. It also asks families to track symptoms with a daily diary to measure whether treatment helps over the study period.
Hot Springs, ArkansasAges 6–17 - NCT03613545RecruitingPhase 2/Phase 3
Fecal transplant to treat irritable bowel syndrome
This study tests whether transferring stool bacteria from a healthy donor (fecal microbiota transplantation) can improve symptoms of irritable bowel syndrome (IBS). It may help by changing the gut bacteria that can influence digestion and gut discomfort.
Guangzhou, GuangdongAges 18–75 - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04217733RecruitingPhase 3
Ethosuximide plus pentoxifylline for IBS belly pain
This Phase 3 study tests whether two medicines (ethosuximide and pentoxifylline) can reduce belly pain from irritable bowel syndrome (IBS). It may help people whose IBS pain has been moderate to severe recently and who can keep their current IBS treatment steady.
TantaAges 18 years+ - NCT05185609Recruiting
Tests anal function in people with inflammatory bowel disease
This study checks how well the anal area works in people with inflammatory bowel disease (IBD), even when your bowel disease is “in remission” but you may still have symptoms. It may help doctors better understand the cause of ongoing problems and guide future care.
ÖrebroAges 18–65 - NCT05525598Recruiting
Online therapy for severe body–mind symptom disorders
This trial tests an internet-based treatment program for people with moderate-to-severe functional somatic disorders (long-lasting physical symptoms linked to how the body and brain interact). It may help reduce symptoms and improve day-to-day functioning by offering structured support online.
Aarhus C, DenmarkAges 18–60 - NCT05680766Recruiting
Exercise training to improve IBS symptoms in inactive people
This trial tests whether a structured exercise program can improve symptoms in people with irritable bowel syndrome (IBS) who currently live a mostly sedentary, inactive lifestyle. It focuses on safety and feasibility (whether the program can be done and what symptom changes may occur).
JetteAges 18–60 - NCT05719246Recruiting
Yoga and meditation for teens with IBS stress
This study tests a structured yoga and meditation program to help reduce stress symptoms in teens with irritable bowel syndrome (IBS). It may help your teen learn calming practices that could ease how stress affects IBS.
Camden, New JerseyAges 12–21 - NCT05721742Recruiting
Virtual diet education for irritable bowel symptom management
This trial tests whether adding online (virtual) diet education to a step-by-step irritable bowel (IBS) care plan can improve symptoms like belly pain and stool changes. You may be asked to make diet changes and use a device to join the virtual education.
Halifax, N.S.Ages 18–65 - NCT05730491Recruiting
Online parenting program for kids with IBS-related belly pain
This trial tests an online social learning program to help parents support their child when the parent has irritable bowel syndrome (IBS) or related belly pain. It may help families build coping skills and resilience through guided parent sessions.
Seattle, WashingtonAges 18 years+ - NCT05740319Recruiting
Test stool transplant to treat irritable bowel syndrome
This trial studies fecal microbiota transplantation, which is transferring stool bacteria from a healthy donor to help rebalance gut microbes. If you have irritable bowel syndrome (IBS) that hasn’t improved after several standard treatments, this study may see whether it reduces your symptoms and is safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05972317Recruiting
Study gut bacteria in IBS patients with and without treatment
This study looks at stool (poop) samples to understand differences in gut bacteria in people with irritable bowel syndrome (IBS), depending on whether they’ve had treatment. It may help researchers find better ways to explain IBS and improve care.
RehovotAges 18–70 - NCT06090110Recruiting
Vagus nerve stimulation for irritable bowel syndrome
This study tests whether a gentle electrical device that stimulates the vagus nerve can help relieve symptoms of irritable bowel syndrome. If you have IBS and are between 18 and 75, you may be able to join.
Maastricht, LimburgAges 18–75 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06268964RecruitingPhase 1/Phase 2
Trimebutine vs probiotics for kids with belly pain
This study compares two treatments—trimebutine and probiotics—to see which works better for children with recurring stomach pain that has no clear medical cause. It aims to find a safe and effective option for kids aged 4 to 18.
ColimaAges 4–18
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Common questions
- Are there clinical trials for irritable bowel syndrome - diarrhoea?
- Yes. Clin2 currently lists 113 recruiting irritable bowel syndrome - diarrhoea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritable bowel syndrome - diarrhoea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritable bowel syndrome - diarrhoea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.