Estradiol skin patch plus exercise for prostate cancer patients on hormone therapy
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This study tests whether using an estradiol skin patch along with a supervised exercise program can reduce the side effects of hormone therapy (androgen deprivation therapy) in men receiving radiation therapy for localized prostate cancer. The goal is to improve quality of life during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a man over 18 years old with localized prostate cancer.
- You are scheduled to receive radiation therapy plus at least 12 months of androgen deprivation therapy (ADT, such as leuprorelin).
- You are able to perform daily activities (ECOG 0-1) and have a body mass index between 18.5 and 30.0.
- You do not have any of the following: distant cancer spread, a pacemaker, a recent heart attack or stroke (within 12 months), a history of blood clots, untreated or unstable other cancer, or a condition preventing regular exercise.
- You are not currently taking glucocorticoids and have no allergies to estradiol, leuprorelin, or the patch ingredients.
- You are willing to participate and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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