Adjuvant radiotherapy for esophageal cancer after immunotherapy
Part of Cancer, Digestive system clinical trials.
This trial tests if adding radiation therapy after surgery improves outcomes for people with esophageal squamous cell cancer who received immunotherapy and chemotherapy before surgery but did not achieve a complete response. It aims to see if this approach can lower the chance of the cancer coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have squamous cell carcinoma of the esophagus that was surgically removed (R0 resection).
- You received 2 cycles of immunotherapy plus chemotherapy before surgery.
- After surgery, the cancer did not completely disappear (non-pCR).
- You are in generally good health, with adequate organ function (kidney, liver, heart, blood counts).
- You agree to use effective contraception if applicable.
- You do not have active autoimmune disease, uncontrolled infections, or a history of chest radiation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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