Lower starting chemo dose for older adults with metastatic colorectal cancer
Part of Cancer, Digestive system clinical trials.
This study tests whether starting with a lower dose of chemotherapy works as well as the standard dose for people aged 70 and older with metastatic colorectal cancer. The goal is to find a treatment that is effective but gentler, with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older
- You have colorectal cancer that has spread to other parts of the body and cannot be treated with local treatments like surgery
- You have not had chemotherapy for metastatic cancer before (but prior chemo for early-stage cancer more than a year ago is okay)
- You do not have certain genetic types like MSI-high colorectal cancer or DPD deficiency
- You have adequate organ function (your doctor will check with blood tests)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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