Clin2
NCT06840977Possibly a fitRecruiting

Low dose chemo for older adults with colorectal cancer

Colon Adenocarcinoma

Part of Cancer, Digestive system clinical trials.

This trial tests a lower-dose chemotherapy regimen for adults aged 70 or older with metastatic colorectal cancer that has not been treated yet. It aims to see if a gentler approach can still be effective and easier to tolerate.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
51 people
Ages
70 years to 99 years
Study type
Observational

Who can take part

  • You are 70 years or older
  • You have been diagnosed with colorectal cancer that has spread to other parts of the body (metastatic) and you have not yet had any treatment for this stage
  • You have a certain level of health and independence, as measured by a specific score (G8 score of 12 or higher)
  • Your tumor type is MSS (meaning it has stable microsatellites) and does not have a BRAF V600E mutation
  • You are able to understand and sign a consent form

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06275958Recruiting· Phase 3
Lower starting chemo dose for older adults with metastatic colorectal cancer

This study tests whether starting with a lower dose of chemotherapy works as well as the standard dose for people aged 70 and older with metastatic colorectal cancer. The goal is to find a treatment that is effective but gentler, with fewer side effects.

's-Hertogenbosch
NCT06888843Recruiting· Phase 2
Chemotherapy for colorectal cancer in patients 70+

This trial tests two chemotherapy drugs, capecitabine alone or with oxaliplatin, in people aged 70 or older after surgery for stage III colorectal cancer. The goal is to find out which treatment works better to prevent cancer from coming back.

Nizhny Novgorod
NCT06293625Recruiting· Phase 3
Chemotherapy before surgery for colon cancer in older adults

This trial tests whether giving 6 weeks of chemotherapy (FOLFOX) before surgery can help people aged 70 and older with locally advanced colon cancer. It aims to make treatment safer and more effective for older adults.

Dijon
NCT06609551Recruiting· Phase 3
ctDNA-guided chemo choice for elderly colon cancer patients

This trial tests whether using a ctDNA blood test can help choose the best chemotherapy after colon cancer surgery for people aged 70–80. It aims to make treatment more personalized and reduce side effects.

Hangzhou, Zhejiang
NCT06665087Not yet recruiting· Phase 2
Radiation and first treatment for older adults with colorectal cancer

This study tests a new way of giving radiation therapy in smaller, more frequent doses along with your first round of systemic treatment (chemo or other drugs) for metastatic colorectal cancer. The goal is to find a treatment that is effective and easier for older or frailer patients to tolerate.

NCT06652412Not yet recruiting· Phase 2
Shorter radiation with medication for older adults with colorectal cancer

This trial tests a shorter course of radiation therapy combined with medication for older or frail patients with colorectal cancer that cannot be removed by surgery. The goal is to control the cancer while reducing side effects and improving quality of life.

Hear when a new Colon Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.