Clin2
NCT06888843Possibly a fitRecruiting

Chemotherapy for colorectal cancer in patients 70+

Colorectal Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests two chemotherapy drugs, capecitabine alone or with oxaliplatin, in people aged 70 or older after surgery for stage III colorectal cancer. The goal is to find out which treatment works better to prevent cancer from coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
160 people
Ages
70 years to 90 years
Study type
Interventional

Who can take part

  • You are 70 years old or older.
  • You have stage III colorectal cancer and have had surgery to remove it.
  • You have not had chemotherapy or other drug treatment for colorectal cancer before.
  • Your overall health is good (able to do daily activities without help).
  • You have no other serious medical conditions or active cancers.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07365592Recruiting· Phase 1/Phase 2
Neoadjuvant therapy for locally advanced colorectal cancer

This trial tests a combination of chemotherapy, an immunotherapy drug (anti-PD-1 antibody), and sitagliptin before surgery for colorectal cancer that has not spread to other organs. The goal is to see if this approach can shrink the tumor and improve outcomes.

Hangzhou, Zhejiang
NCT07653685Not yet recruiting· Phase 1/Phase 2
Testing TQB2930 plus chemo for advanced colorectal cancer

This trial tests a new drug, TQB2930, combined with chemotherapy (with or without bevacizumab) for advanced colorectal cancer that cannot be removed by surgery. It's designed for people whose tumors are HER2-positive and have not responded to standard treatments.

Beijing, Beijing Municipality
NCT06405139Recruiting· Phase 2
Chemo combo (nanoliposomal irinotecan, oxaliplatin, capecitabine) before surgery for locally advanced colorectal cancer

This trial tests a combination of three chemotherapy drugs (nanoliposomal irinotecan, oxaliplatin, and capecitabine) given before surgery to shrink locally advanced colorectal cancer that cannot be treated with radiation. The goal is to make the tumor removable with a better chance of complete removal (R0 resection).

Beijing
NCT06385418Recruiting· Phase 2
Colon chemotherapy for colorectal cancer

This trial tests putting a chemo drug (fluorouracil) directly into the colon through a tube. It's for people with colorectal cancer who are already getting other cancer treatment, to see if adding local chemo helps shrink the main tumor.

Nanjing, Jiangsu
NCT07562503Recruiting· Phase 2
Blood Test to Guide Colorectal Cancer Follow-Up Treatment

This trial tests whether a special blood test that detects cancer DNA can help doctors decide if you need additional chemotherapy after colorectal cancer surgery. The goal is to personalize treatment based on your individual risk rather than giving chemotherapy to everyone.

Shanghai
NCT02355379Recruiting· Phase 3
Chemo after colon cancer surgery for adults 70 and older

This Phase 3 trial studies whether giving chemotherapy after surgery helps people age 70+ with stage III colon cancer. You would be compared to another planned treatment approach, aiming to lower the chance of the cancer coming back.

Fort de France, Guadeloupe

Hear when a new Colorectal cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.