Pembrolizumab for brain infection in people with weakened immune systems
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This trial tests if pembrolizumab, an immunotherapy drug, can help fight a rare brain virus called PML in people whose immune systems are weakened but not due to HIV. The goal is to see if it improves recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have been diagnosed with PML (a brain infection) less than 2 months ago.
- The virus causing PML must be found in your spinal fluid.
- You cannot have HIV, multiple sclerosis, or certain autoimmune diseases that might improve with standard treatment.
- You must not be pregnant, plan to become pregnant, or breastfeed during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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