Nerve stimulation for stubborn anxiety
Part of Mental health clinical trials.
This study tests a new, non-invasive treatment using mild electrical stimulation on a nerve in your face (trigeminal nerve) to help with anxiety that hasn't improved with other treatments. It aims to see if this approach is safe and helpful for people with generalized anxiety disorder who have not responded to standard medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with generalized anxiety disorder (GAD).
- You are currently on a stable dose of an SSRI or SNRI medication (like Zoloft, Paxil, Effexor, etc.) for at least 8 weeks.
- You have tried at least two different anxiety medications from different classes for 8 weeks or more, and they didn't work well enough (treatment-resistant).
- You do not have moderate to severe depression, high suicide risk, or certain other mental health conditions (like bipolar disorder, OCD, PTSD, schizophrenia).
- You do not have certain medical conditions (like epilepsy, trigeminal neuralgia, dementia, or implanted electrical devices).
- You are not pregnant or breastfeeding, and you do not use cannabis, illegal drugs, or drink more than 3 alcoholic drinks per week.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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