Diabetes and medication effects on uterine muscle during C-section
Treatments studied
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This trial studies how three medications (ephedrine, phenylepinephrine, and norepinephrine) affect the contraction strength of uterine muscle tissue from pregnant people with type 2 or gestational diabetes during planned C-sections. It aims to understand if these drugs act differently in people with diabetes, which could help tailor safer treatments for low blood pressure during surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 19 and 45 years old.
- You are between 37 and 41 weeks pregnant.
- You have type 2 diabetes or gestational diabetes (or, for a healthy comparison group, no diabetes).
- You are not in labor and have not received oxytocin (a labor-inducing drug).
- You are scheduled for a planned first or second C-section under spinal anesthesia.
- You do not have conditions that raise bleeding risk like preeclampsia, twins, or a very large baby, unless these are related to your diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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