Testing suvorexant for alcohol use disorder
Treatments studied
Part of Mental health clinical trials.
This study tests whether the sleep medication suvorexant can help people with alcohol use disorder drink less. It involves a short stay where you'll receive either suvorexant or a placebo and then have alcohol.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 55 years old.
- You have had at least 4 drinks (if female) or 5 drinks (if male) in about 2 hours in the last month.
- You have been diagnosed with moderate or severe alcohol use disorder.
- You are not currently seeking treatment for your drinking.
- You are not taking any prescription medications except birth control.
- You do not have sleep apnea or a history of allergic reaction to suvorexant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a medicine called suvorexant, which is used for sleep, can help people with alcohol use disorder drink less, especially when stressed. You would receive the medicine or a placebo, and researchers will track your drinking and stress levels over several weeks.
This study tests whether a medication called daridorexant can help people with alcohol use disorder who also have trouble sleeping. The drug works by helping you fall asleep and stay asleep, which may reduce cravings to drink.
This trial tests if the sleep medication daridorexant can help people who have both insomnia and alcohol use disorder. It looks at whether the drug improves sleep and reduces drinking.
This Phase 1 study looks at sex differences in how the body and brain respond when people stop drinking alcohol for a short time. You may be asked to complete questionnaires and provide blood samples to measure changes during the abstinence period.
This study tests whether brexpiprazole can help adults with alcohol use disorder. You must currently not be taking alcohol-focused treatment or alcohol medicines, and you’ll likely complete questionnaires and brain scans.
This study tests whether a new medication called NTX-2001 can help people with alcohol use disorder drink less. Researchers will measure how the drug affects alcohol consumption and safety in adults aged 21–60.
Hear when a new Alcohol Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.