Clin2
NCT07532252Likely a fitNot yet recruiting

Daridorexant for Alcohol Use Disorder and Sleep Problems

Alcohol Use Disorder

Treatments studied

Part of Mental health clinical trials.

This study tests whether a medication called daridorexant can help people with alcohol use disorder who also have trouble sleeping. The drug works by helping you fall asleep and stay asleep, which may reduce cravings to drink.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have moderate or severe alcohol use disorder (drinking that's hard to control)
  • You have significant sleep problems (trouble falling or staying asleep most nights)
  • You are at least 18 years old and fluent in English
  • You genuinely want to reduce or quit drinking—not just doing this because someone else told you to
  • You have internet access to attend virtual check-ins from home
  • If you're a woman who could become pregnant, you agree to use reliable birth control during the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07701928Not yet recruiting· Phase 2
Daridorexant for sleep and alcohol use disorder

This trial tests if the sleep medication daridorexant can help people who have both insomnia and alcohol use disorder. It looks at whether the drug improves sleep and reduces drinking.

Spokane, Washington
NCT06326684Recruiting· Early Phase 1
Testing suvorexant for alcohol use disorder

This study tests whether the sleep medication suvorexant can help people with alcohol use disorder drink less. It involves a short stay where you'll receive either suvorexant or a placebo and then have alcohol.

Lexington, Kentucky
NCT07214207Recruiting· Phase 2
Testing a sleep medicine for alcohol use disorder and stress-related drinking

This trial tests whether a medicine called suvorexant, which is used for sleep, can help people with alcohol use disorder drink less, especially when stressed. You would receive the medicine or a placebo, and researchers will track your drinking and stress levels over several weeks.

Columbus, Ohio
NCT06629259Recruiting· Phase 2
Guanfacine for Alcohol Use Disorder

This trial tests if guanfacine, a medication that calms certain brain signals, can help people reduce or stop drinking. You may qualify if you have moderate to severe alcohol use disorder and want to quit.

Indianapolis, Indiana
NCT07325266Recruiting· Phase 2
Testing apremilast for alcohol use disorder

This study tests whether a pill called apremilast can help reduce drinking in people with alcohol use disorder. You'll take the medication and attend regular visits to see how it affects your alcohol cravings and use.

Los Angeles, California
NCT07029529Recruiting· Phase 2
Apremilast for alcohol use disorder

This study tests whether a drug called apremilast can help people who drink heavily reduce their alcohol use. You will take the medication daily for several weeks and attend study visits to track your progress.

New Haven, Connecticut

Hear when a new Alcohol Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.