Clin2
NCT06327178Possibly a fitRecruiting

Sbrt and Immunotherapy for Advanced Kidney Cancer

Systemic Anti-tumor Activity and Safety of the Combination of SBRT and Concurrent PD-1 Blockade in Metastatic RCC

Part of Cancer, Immune system & allergy clinical trials.

This trial studies whether combining a special type of radiation (SBRT) with an immunotherapy (PD-1 blocker) can shrink kidney cancer that has already spread. It is for people who have already had this combination treatment before.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 or older.
  • You have advanced kidney cancer that has spread (stage IV).
  • You have already received SBRT (a precise type of radiation) together with a PD-1 blocker (an immune therapy) for your kidney cancer.
  • You have tumors that can be seen and measured on imaging scans.
  • You do not have another cancer that is getting worse or needs active treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06794086Recruiting· Phase 3
SBRT and immunotherapy for colorectal cancer liver metastases

This trial combines targeted radiation (SBRT) with an immunotherapy drug (PD-1 inhibitor) to treat colorectal cancer that has spread to the liver and can't be removed by surgery. It aims to help shrink or control tumors in patients whose cancer has a normal DNA repair system (pMMR/MSS).

Guangzhou, Guangdong
NCT06889649Recruiting· Phase 2
SBRT plus immunotherapy and targeted therapy for kidney cancer

This trial tests a combination of targeted therapy (axitinib) and immunotherapy (toripalimab) alongside stereotactic body radiation therapy (SBRT) for kidney cancer that has come back or spread. It may be an option if you have a limited number of metastatic tumors that can be treated with radiation.

Beijing, Beijing Municipality
NCT06583070Recruiting
SABR plus targeted therapy and immunotherapy for advanced kidney cancer

This trial tests combining a precise type of radiation (SABR) with standard targeted therapy and immunotherapy drugs for kidney cancer that has come back or spread. The goal is to see if adding radiation improves outcomes.

Beijing, Beijing Municipality
NCT07470840Not yet recruiting· Phase 2
Radiation plus two drugs for advanced kidney cancer

This trial tests whether combining focused radiation (SBRT) with anlotinib and bimepolizumab can shrink or slow kidney cancer that has spread and cannot be surgically removed. It's designed for people with a specific type of kidney cancer who are generally healthy enough to handle these treatments.

Fuzhou, Fujian
NCT06255223Recruiting· Phase 2
Radiation therapy plus immunotherapy for advanced kidney cancer

This trial tests a combination of targeted radiation therapy with a restart of immunotherapy for people whose kidney cancer has grown after prior immunotherapy. It aims to see if radiation can help the immune system fight the cancer again.

Nanjing, Jiangsu
NCT04974671Recruiting· Phase 2
SBRT radiation for limited cancer growth on immunotherapy

This trial tests whether targeted external-beam radiation (SBRT) can control a small number of progressing kidney cancer spots while you continue immune checkpoint inhibitor immunotherapy. It may help shrink or stop those specific “oligoprogressive” lesions and prolong benefit from your current immunotherapy.

New Haven, Connecticut

Hear when a new Systemic Anti-tumor Activity and Safety of the Combination of SBRT and Concurrent PD-1 Blockade in Metastatic RCC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.