Immunotherapy plus fasting diet and vitamin C for KRAS-mutated colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of two immunotherapy drugs (botensilimab and balstilimab) plus a fasting-mimicking diet and high-dose vitamin C for people with a specific type of advanced colorectal cancer (KRAS-mutated). It aims to see if this approach can help when standard treatments have stopped working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your colorectal cancer has spread to other parts of the body (like the liver or lungs) and has a change in the KRAS gene.
- You have already tried at least one type of standard chemotherapy, and it either didn't work, caused side effects, or you couldn't take it.
- You are 18 years or older, able to care for yourself, and have a life expectancy of at least 3 months.
- You don't have diabetes, and you are not currently taking vitamin C supplements.
- You are willing to follow a special fasting-mimicking diet during the study, and you can safely stop certain medications during the fasting periods.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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