Nefopam for pain after hip replacement surgery
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests if adding nefopam to standard painkillers (paracetamol and ketoprofen) improves pain right after hip replacement surgery and reduces long-term pain. It aims to give better pain relief with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can speak French.
- You are scheduled for a hip replacement (first-time or revision).
- You will receive paracetamol and ketoprofen for pain after surgery.
- You will have general or spinal anesthesia (but not spinal morphine).
- You are covered by French social security and can give written consent.
- You do not have conditions like glaucoma, prostate problems, severe liver or heart disease, kidney failure, or a history of seizures or stomach bleeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a single dose of methadone given during hip replacement surgery can better control pain and reduce the need for other opioid painkillers afterward. It may help you recover with less pain and fewer side effects.
This study compares two ways of managing pain during hip replacement surgery: one that reduces the use of strong painkillers (opioids) using a special monitor, and one that avoids them altogether. The goal is to see which approach controls pain better with fewer side effects.
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
This study tests a pain reliever called nefopam, given as a tablet, for people with sudden pain from rheumatology conditions (joint, muscle, or bone problems). The goal is to learn how the drug works in the body, and it might help improve pain management for patients like you.
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Hear when a new Total Hip Arthroplasty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.