Brain and Opioid Use Study
Part of Mental health clinical trials.
This study uses brain scans to understand how adversity affects opioid use and recovery. It compares people with opioid use disorder on buprenorphine, people taking buprenorphine for chronic pain, and healthy volunteers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be fluent in English and able to give consent.
- You must be able to have an MRI scan (no metal implants, no claustrophobia).
- You cannot be pregnant or have a serious medical condition like stroke or seizures.
- If you are in the opioid use disorder group, you must be diagnosed with OUD, taking buprenorphine, and have been free from illicit drugs for at least 2 weeks.
- If you are in the control group taking buprenorphine for pain, you must not have a substance use disorder.
- If you are a healthy volunteer, you cannot be taking buprenorphine or have any psychiatric or major medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses brain scans (MRI) to understand how pain affects people with opioid use disorder or regular opioid use, compared to healthy volunteers. It aims to find better ways to treat both pain and opioid addiction.
This study tests whether brain scans and thinking tests can help understand opioid use disorder. It is for people on stable buprenorphine or methadone treatment.
This study uses MRI scans over time to track brain changes in people with opioid use disorder who recently started methadone treatment. You can help researchers understand recovery patterns if you are early in your methadone journey and can commit to repeated visits.
This trial tests if brain stimulation can help people starting buprenorphine for opioid use disorder. It aims to improve treatment outcomes and support recovery.
This trial tests a brain-training program for people with opioid use disorder. It uses an EEG headset to measure brain activity while you do computer exercises, and aims to see if this training can help recovery.
This trial combines a gentle brain stimulation technique called tDCS with thinking exercises to see if it helps people with opioid use disorder who are already on medication. It aims to improve treatment outcomes
Hear when a new Opioid Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.