Alcohol injection with ablation for persistent atrial fibrillation

This study tests whether applying a small amount of alcohol to a specific heart vein (“vein of Marshall”) is safe and feasible during a standard atrial fibrillation (AF) ablation. It may help improve AF treatment, but the goal here is mainly to see if the approach can be done safely in the right patients.

This study tests a new approach to catheter ablation for people with persistent atrial fibrillation (a type of irregular heartbeat). It may be an option if you have not responded well to or could not tolerate a rhythm-control medication.

This trial is testing a new way to treat atrial fibrillation by using a catheter to target the specific areas in the heart that trigger the irregular heartbeat. If you have persistent atrial fibrillation and haven't had prior catheter ablation, you may be eligible to join.

This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.

This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.

This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.