Atrial fibrillation ablation using two different energy types
Part of Heart & circulation clinical trials.
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older.
- You have paroxysmal atrial fibrillation, with at least one episode recorded in the past 12 months (ECG, Holter, a heart monitor, or a loop recorder).
- You can read, understand, and sign the informed consent form.
- You do NOT have persistent or permanent atrial fibrillation.
- You have not had prior left atrial ablation or left atrial heart surgery, and you have no prior AF/related ablation history.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares two ways to treat persistent atrial fibrillation (an irregular heartbeat that lasts for months or years). One method uses pulsed field energy and the other uses radiofrequency heat to fix the heart's electrical signals. The goal is to see which method is safer and more effective for patients having their first ablation procedure.
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This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
This trial is testing a specific approach to catheter ablation for people with persistent atrial fibrillation. It aims to improve how abnormal heart tissue is targeted to help restore a normal rhythm.
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This study compares different ways of doing a procedure called catheter ablation to treat a type of atrial fibrillation that lasts longer than 7 days. They want to see if adding an extra step to the standard treatment helps more than just doing the standard treatment alone. If you join, you will be randomly assigned to one of the three treatment groups.
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