Clin2
NCT06369350Possibly a fitNot yet recruiting

Vitamin B6 and blood flow during leg exercise

Ischemia Reperfusion InjuryPeripheral Artery Disease

Treatments studied

Part of Heart & circulation clinical trials.

This study tests whether taking vitamin B6 changes how your body responds to exercise when blood flow to the leg is temporarily reduced. It may help researchers understand how to improve blood flow and exercise responses in people with circulation problems.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
30 people
Ages
21 years to 70 years
Study type
Interventional

Who can take part

  • You are between 21 and 70 years old.
  • You are generally healthy, with no ongoing or chronic medical conditions.
  • You do not smoke.
  • You are not taking medications for blood pressure or heart conditions (like beta blockers or ACE inhibitors).
  • You are not taking vitamin B6 supplements, B-complex vitamins, or multivitamins with B6.
  • You are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06686121Recruiting· Phase 3
Walking recovery after leg artery treatment

This study tests whether a home-based exercise program or a special beetroot drink can help people walk better after having a procedure to improve blood flow in their legs. It aims to find ways to boost mobility and quality of life.

Tucson, Arizona
NCT05465070Recruiting
Heat therapy trial for leg blood-flow problems

This trial studies whether applying heat to your legs can improve symptoms and function in people with peripheral artery disease (reduced blood flow to the legs). You may be tested with a simple blood-flow check and an MRI scan, depending on eligibility.

Indianapolis, Indiana
NCT04252950Recruiting
Exercise program after blood-flow procedures for leg artery disease

This study tests whether a community-based exercise program helps people recover and improve walking after a procedure to restore blood flow in the leg arteries. It may help if your main problem is leg circulation problems and you’re able to take part in exercise safely.

Minneapolis, Minnesota
NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries

This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.

Chicago, Illinois
NCT07866651Not yet recruiting
Exercise study: sex differences in leg blood flow and muscle energy

This study looks at how men's and women's leg muscles and blood flow respond to hard exercise. You do two cycling tests and a small leg biopsy (taking a tiny muscle sample) to help researchers understand why energy use differs between sexes.

Vancouver, British Columbia
NCT07782671Not yet recruiting· Phase 3
Walking and a vitamin B3 supplement for peripheral artery disease

This trial tests a vitamin B3 supplement (nicotinamide riboside) combined with a walking program to see if it helps improve walking ability in people with peripheral artery disease (blocked leg arteries). If you qualify, you may get the supplement or a placebo along with supervised exercise.

Hear when a new Ischemia Reperfusion Injury trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.