Clin2
NCT06382519Possibly a fitRecruiting

Thalidomide for Very Early-Onset IBD in Kids

Inflammatory Bowel Diseases

Treatments studied

Part of Digestive system clinical trials.

This study tests whether the drug thalidomide can help children with very early-onset inflammatory bowel disease (VEOIBD) when their symptoms are moderate to severe. It aims to see if thalidomide can calm the inflammation and improve quality of life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
40 people
Ages
4 weeks to 6 years
Study type
Observational

Who can take part

  • You have been diagnosed with inflammatory bowel disease (IBD).
  • Your IBD symptoms started before you were 6 years old.
  • Your disease is currently moderate to severe, meaning you have significant symptoms like belly pain, frequent diarrhea, or blood in stool.
  • You and your family are willing to try thalidomide as a treatment and be part of this study.
  • You have not taken thalidomide in the last 30 days or a biologic medication (like infliximab or adalimumab) in the last 8 weeks.
  • You do not have liver problems, nerve damage, blood clots, or an allergy to thalidomide.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03571373Recruiting
Study of new childhood IBD and tracking safety

This trial collects information from children who are newly diagnosed with inflammatory bowel disease (IBD) and follows them to understand safety in real life. It may help doctors improve early diagnosis and treatment planning for kids with IBD.

Rotterdam
NCT05043870Recruiting· Phase 4
Testing medicines that calm the immune system in kids with Crohn’s

This trial studies a combination of immune-suppressing treatments for children with Crohn’s disease that is not well controlled. It may help reduce inflammation and improve symptoms if you meet the study’s disease-activity and safety requirements.

Shanghai, Shanghai Municipality
NCT06268093Recruiting· Phase 2
Testing thalidomide for syringomyelia

This trial tests whether the drug thalidomide can help people with syringomyelia (a fluid-filled cyst in the spinal cord) who cannot have standard surgery or for whom surgery didn't work. It aims to see if thalidomide can slow or improve symptoms.

Beijing, Beijing City
NCT07476625Not yet recruiting
Thalidomide for children with PFAPA fever

This trial tests whether the drug thalidomide can reduce fever episodes in children with PFAPA syndrome. It may help children who still get frequent fevers even though steroids work temporarily.

NCT06530576Recruiting· Phase 2
Thalidomide for symptomatic large granular lymphocytic leukemia

This trial tests the drug thalidomide for people with symptomatic large granular lymphocytic leukemia (LGLL), a rare blood cancer. It aims to see if thalidomide can help control the disease and improve symptoms like low blood counts or an enlarged spleen.

Tianjin, Tianjin Municipality
NCT06617182Recruiting· Phase 2
Thalidomide and glutamine for radiation bowel injury

This trial tests whether combining thalidomide and glutamine helps people with bleeding caused by past radiation treatment to the abdomen or pelvis. The medication may reduce inflammation and help healing.

Xi'an, Shaanxi

Hear when a new Inflammatory Bowel Diseases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.