Thalidomide and glutamine for radiation bowel injury
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether combining thalidomide and glutamine helps people with bleeding caused by past radiation treatment to the abdomen or pelvis. The medication may reduce inflammation and help healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have bleeding from the rectum or bloody stools after cancer radiation therapy
- Bleeding happens at least 1 out of 5 times you have a bowel movement
- You are able to care for yourself and are out of bed more than half the day (ECOG 0-2)
- You do not have active cancer in the stomach or intestines
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how a natural gut hormone called GLP-2 changes in your blood after radiation treatment for cancer in the belly or pelvic area, and whether it relates to gut irritation (radiation enteritis). It may help doctors understand and better manage radiation side effects.
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
This trial tests the drug thalidomide for people with symptomatic large granular lymphocytic leukemia (LGLL), a rare blood cancer. It aims to see if thalidomide can help control the disease and improve symptoms like low blood counts or an enlarged spleen.
This trial compares two treatments for anemia caused by abnormal blood vessels in the stomach (GAVE) in people with cirrhosis. It tests whether a medicine called thalidomide is better than a procedure that uses a tiny argon plasma beam to stop bleeding, to see which helps treat anemia more effectively.
This study tests whether the drug thalidomide can help children with very early-onset inflammatory bowel disease (VEOIBD) when their symptoms are moderate to severe. It aims to see if thalidomide can calm the inflammation and improve quality of life.
This trial tests whether a steroid enema (dexamethasone) can help prevent or reduce bowel damage caused by radiation therapy for rectal cancer. If you're starting or recently started radiation for rectal cancer, this may help protect your bowel health.
Hear when a new Radiation Enteritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.