Personalized brain stimulation for hard-to-treat depression
Part of Mental health clinical trials.
This study tests a new, personalized form of brain stimulation (called TMS) using MRI scans to target the right areas for people whose depression hasn't improved with medication. It aims to see if this tailored approach works better than standard TMS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years or older.
- You have major depression that didn’t get better after trying at least one antidepressant medication for 4 weeks.
- You do not have a psychotic disorder, substance abuse, or high suicide risk.
- You don’t have metal in your head, a pacemaker, or other implanted electronic device.
- You are not pregnant and can have an MRI scan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses brain imaging to guide a noninvasive treatment called transcranial magnetic stimulation (TMS) for people with depression. It aims to see if tailoring the stimulation to each person's brain can improve symptoms.
This trial tests a faster version of a brain stimulation treatment called TMS for people with depression. The goal is to see how well it works and how tolerable it is.
This trial tests a new type of transcranial magnetic stimulation (TMS) for people with severe depression that hasn't improved with multiple medications or therapy. It uses a different frequency pattern to target brain circuits.
This trial tests an accelerated form of TMS (a treatment that uses magnetic pulses to stimulate the brain) for people with severe depression who have recently been in a psychiatric hospital. It aims to see if a faster schedule of TMS can help improve symptoms quickly.
This study tests a new way to use magnetic brain stimulation (TMS) to treat depression and anxiety that haven't improved with medication. The treatment is personalized based on your brain scans, which may make it more effective.
This study tests a personalized, maintenance brain-stimulation treatment (called accelerated TMS) that is fine-tuned for each person to help keep depression from coming back. It also uses wrist-worn sensors and phone surveys to track mood and catch signs of depression early so you can get help sooner.
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.