Phage therapy for recurrent UTIs in kidney transplant patients
Treatments studied
Part of Infections, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a phage (virus that kills bacteria) treatment for women who have had a kidney transplant and keep getting urinary tract infections (UTIs) caused by E. coli bacteria. It aims to see if this therapy can help prevent future infections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older who has had a kidney transplant.
- You have had at least 2 UTIs in the last 6 months or 3 in the last year, all caused by E. coli bacteria.
- You can take the study medicine yourself or have a family member help you.
- If you can become pregnant, you must use effective birth control starting 1 month before the study and for 6 months after treatment ends.
- You are willing to follow all study procedures and be available for the entire study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects medical data from people with urinary tract infections (UTIs) to help future research and improve how UTIs are treated. You may be eligible if you have symptoms of a UTI now or have had them in the past.
This trial tests whether specially designed viruses (called phages) can safely and effectively treat drug-resistant urinary tract infections. The phages are delivered directly into your bladder or kidney through a small tube, and the goal is to eliminate the infection when standard antibiotics have failed.
This trial tests whether a special virus (bacteriophage) that attacks E. coli bacteria can help control bacteria in the bladder without causing an infection. It's for people with spinal cord injury who use a catheter and have E. coli in their urine but no active infection.
This study looks at whether continuing an antibiotic called TMP-SMX (Bactrim) for longer helps prevent urinary tract infections after a kidney transplant. If you've already taken it safely for 6 months, you may qualify to continue it for another 6 months or stop, to see which is better.
This study tests whether giving an antibiotic after a kidney transplant can prevent bloodstream infections. Participants who have bacteria in their urine in the first month after transplant may be eligible.
This study looks at bacteria in urine samples from people who get frequent urinary tract infections and have a certain type of catheter. It aims to learn why some bacteria are hard to treat and may help improve care for patients like you.
Hear when a new Urinary Tract Infection, Recurrent trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.