Brain scan study of emotion and a common antidepressant
Part of Mental health clinical trials.
This study uses a powerful MRI scanner to look at how a part of the brain called the amygdala responds to emotional tasks, and whether a common antidepressant called citalopram affects that response. It may help researchers understand how these treatments work for mental health conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be able to give informed consent and speak English well enough to complete the tasks.
- You must have no metal in your body (like implants or shrapnel) that would make an MRI unsafe.
- You must not have a current or past major psychiatric condition (like major depression) or a significant personality disorder.
- You must not have ADHD or autism that affects daily life or requires medication.
- You must not be taking any psychiatric medications now or in the last 3 months.
- You must not have medical conditions that conflict with citalopram, such as heart problems, diabetes, epilepsy, or glaucoma.
- You must not be pregnant, planning pregnancy, or breastfeeding.
- You must not have used recreational drugs, smoked more than 5 cigarettes a day, or drunk more than 6 caffeinated drinks daily in the last 3 months.
- You must have a body mass index between 17 and 35.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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