Testing IBI3005 for advanced solid tumors
Part of Cancer clinical trials.
This trial tests an experimental drug called IBI3005 for people whose solid tumors (cancers that form lumps) have continued to grow despite treatment with a specific targeted therapy (EGFR TKI). The goal is to see if IBI3005 can help when other treatments have stopped working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of cancer (a solid tumor) that cannot be removed by surgery or has spread to other parts of the body.
- You have already tried a specific type of targeted therapy (a third-generation EGFR TKI) and your cancer got worse during treatment.
- If you have other genetic changes in your tumor (like METex14), you must have also tried targeted therapy for that and it stopped working.
- You cannot have active serious infections like HIV, uncontrolled hepatitis B or C, active tuberculosis, or active COVID-19 with symptoms.
- You must not have received a live vaccine in the last 4 weeks, and you cannot plan to get one during the study.
- You should not have serious heart problems, uncontrolled high blood pressure, or a recent history of major bleeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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