Clin2
NCT06418945Possibly a fitNot yet recruiting

Dental cleaning after esophageal cancer surgery to improve outcomes

Evaluate the DFS of Patients With Esophageal Cancer Who Underwent Radical Operation After Regular Removal of Porphyromonas Gingivalis

Part of Cancer, Mouth & dental clinical trials.

This study tests whether a special dental cleaning plus an antibiotic (tinidazole) can improve your recovery and long-term outlook after esophageal cancer surgery, by removing a type of mouth bacteria that may affect cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
500 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You must be 18 to 85 years old.
  • You must have been diagnosed with esophageal cancer that can be removed with surgery.
  • You must have had the surgery to remove the cancer within the past 28 days, and the surgery must have completely removed the tumor.
  • You must be in generally good health, with no major problems with your blood counts, liver, or kidneys.
  • You must not need radiation therapy or chemotherapy as part of your treatment plan.
  • You must be willing to avoid alcohol and be able to stop drinking during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05865743Recruiting· Phase 3
Antibiotic cloth before surgery to prevent esophagus infection

This Phase 3 trial tests whether using an antibiotic decolonization treatment around the time of esophagus surgery can reduce serious infections afterward. It may help you lower the risk of postoperative infectious complications after curative esophagectomy or esophagus reconstruction.

Leuven
NCT07799077Not yet recruiting· Phase 2
Chemotherapy and immunotherapy before surgery for esophageal cancer

This study tests a combination of two chemotherapy drugs (paclitaxel and cisplatin) plus an immunotherapy drug (sintilimab) given before surgery for esophageal cancer. The goal is to see if this approach shrinks the tumor and improves outcomes.

Hebei, Shijiazhuang
NCT06692270Not yet recruiting· Phase 2
Immunotherapy before surgery for esophageal cancer

This trial tests whether giving an immunotherapy drug called tislelizumab before surgery helps shrink esophageal cancer and improve outcomes. It is for people newly diagnosed with early-stage squamous cell esophageal cancer that can be removed surgically.

NCT04821843Recruiting· Phase 3
Study before-surgery treatments for esophageal cancer

This Phase 3 trial compares different “treatments before surgery” for people with esophageal (or esophagus-to-stomach) cancer. It aims to see which approach works better to control the cancer and improve outcomes after surgery.

Beijing
NCT06160557Enrolling by invitation
Radiation after endoscopic surgery for superficial esophageal cancer

This trial tests if adding radiation therapy after endoscopic surgery (ESD) helps people with early-stage esophageal cancer that had certain high-risk features, like deeper invasion or positive margins. It aims to improve outcomes for those who didn't get a complete cure with surgery alone.

Fuzhou, Fujian
NCT07530549Not yet recruiting· Phase 2
Study drug for esophageal cancer after initial treatment stops working

This study tests a new treatment for people with locally advanced esophageal cancer that did not respond to initial chemotherapy and immunotherapy. The goal is to see if the study drug can shrink or control the cancer when surgery is not an option.

Hear when a new Evaluate the DFS of Patients With Esophageal Cancer Who Underwent Radical Operation After Regular Removal of Porphyromonas Gingivalis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.