Clin2
NCT06423599Possibly a fitRecruiting

Weight Loss for Obesity and Heart Failure

Heart Failure With Reduced Ejection FractionObesityWeight LossChronic Heart Failure

Treatments studied

Part of Hormones & metabolism clinical trials.

This study tests whether weight loss from a medication can improve how you feel, move, and how well your heart works. It's for people who have both obesity and heart failure with reduced pumping strength.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • Your BMI is 30 or higher (obesity range).
  • You have heart failure with a reduced ejection fraction (EF ≤ 40%) — this means your heart doesn't pump blood as well as it should.
  • You have been on stable, recommended heart failure medications for at least 4 weeks.
  • You have not had a heart attack, stroke, or related hospital stay in the last 6 months.
  • You do not have type 1 diabetes, and you have not taken a GLP-1 drug (like Ozempic) in the past 3 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06909006Not yet recruiting· Phase 3
Semaglutide for adults with type 1 diabetes and overweight

This study tests whether semaglutide, a medicine that helps control blood sugar and reduce weight, can benefit adults with type 1 diabetes who are overweight. If you qualify, you may receive the drug or a placebo, and the study team will monitor your health closely.

Hillerød, Denmark
NCT06825793Not yet recruiting
Semaglutide for weight loss in obesity

This study tests a medication called semaglutide (a once-weekly injection) to help people with obesity lose weight. It is for adults who have already tried lifestyle changes without success.

NCT07770841Recruiting· Phase 3
Oral medication for weight loss study

This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.

Birmingham, Alabama
NCT06633783Not yet recruiting· Phase 3
Weekly shot for weight loss in adults with obesity

This study tests a weekly injection called semaglutide to see how well it helps people with obesity lose weight, compared to a similar approved medicine, Wegovy. It may be an option if you have struggled to lose weight in the past.

Xuancheng, Anhui
NCT07767175Recruiting· Phase 1
Weight loss study for adults with overweight or obesity

This study tests an investigational medication, called NNC0721-8060, to see how it works in people with excess weight (overweight or obesity). It may help with weight loss, but is still in early human testing.

Lenexa, Kansas
NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity

This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.

St Louis, Missouri

Hear when a new Heart Failure With Reduced Ejection Fraction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.